TargetMol

LY2562175

Product Code:
 
TAR-T15806
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T15806-1mg1mg£201.00
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TAR-T15806-2mg2mg£257.00
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TAR-T15806-5mg5mg£348.00
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TAR-T15806-1mL1 mL * 10 mM (in DMSO)£389.00
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TAR-T15806-10mg10mg£510.00
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TAR-T15806-25mg25mg£782.00
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TAR-T15806-50mg50mg£1,026.00
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TAR-T15806-100mg100mg£1,380.00
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This product comes from: United States.
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Further Information

Bioactivity:
LY2562175 is an effective and selective FXR agonist (EC50: 193 nM).
CAS:
1103500-20-4
Formula:
C28H27Cl2N3O4
Molecular Weight:
540.44
Pathway:
Metabolism; Autophagy
Purity:
0.9996
SMILES:
Cn1cc(C(O)=O)c2ccc(cc12)N1CCC(CC1)OCc1c(onc1-c1c(Cl)cccc1Cl)C1CC1
Target:
FXR; Autophagy

References

1. Genin MJ, et al. Discovery of 6-(4-{[5-Cyclopropyl-3-(2,6-dichlorophenyl)isoxazol-4-yl]methoxy}piperidin-1-yl)-1-methyl-1H-indole-3-carboxylic Acid: A Novel FXR Agonist for the Treatment of Dyslipidemia. J Med Chem. 2015 Dec 24;58(24):9768-72.