TargetMol

Lotilaner

Product Code:
 
TAR-T15775
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T15775-1mg1mg£138.00
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TAR-T15775-2mg2mg£168.00
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TAR-T15775-5mg5mg£230.00
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TAR-T15775-1mL1 mL * 10 mM (in DMSO)£286.00
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TAR-T15775-10mg10mg£334.00
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TAR-T15775-25mg25mg£570.00
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TAR-T15775-50mg50mg£838.00
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TAR-T15775-100mg100mg£1,187.00
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TAR-T15775-200mg200mg£1,581.00
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TAR-T15775-500mg500mg£2,344.00
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This product comes from: United States.
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  • Further Information
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Further Information

Bioactivity:
Lotilaner is a parasiticide. It is used as a potent non-competitive antagonist of insects GABACl receptors (IC50 of 23.84 nM for Drosophila melanogaster GABA receptor). It also has no effect on a dog GABAA receptor.
CAS:
1369852-71-0
Formula:
C20H14Cl3F6N3O3S
Molecular Weight:
596.75
Pathway:
Membrane transporter/Ion channel; Microbiology/Virology; Neuroscience
Purity:
0.9932
SMILES:
Cc1cc(sc1C(=O)NCC(=O)NCC(F)(F)F)C1=NO[C@@](C1)(c1cc(Cl)c(Cl)c(Cl)c1)C(F)(F)F
Target:
GABA Receptor; Parasite

References

1. Lotilaner, et al. The novel isoxazoline ectoparasiticide lotilaner (Credelio?): a non-competitive antagonist specific to invertebrates ?-aminobutyric acid-gated chloride channels (GABACls). Parasit Vectors. 2017 Nov 1;10(1):530.