TargetMol

FN-1501

Product Code:
 
TAR-T15335
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T15335-1mg1mg£138.00
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TAR-T15335-5mg5mg£229.00
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TAR-T15335-1mL1 mL * 10 mM (in DMSO)£252.00
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TAR-T15335-10mg10mg£369.00
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TAR-T15335-25mg25mg£576.00
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TAR-T15335-50mg50mg£790.00
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Quantity:
TAR-T15335-100mg100mg£1,050.00
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Further Information

Bioactivity:
FN-1501 is a potent FLT3 and CDK inhibitor (IC50s: 2.47, 0.85, 1.96, and 0.28 nM for CDK2/cyclin A, CDK4/cyclin D1, CDK6/cyclin D1 and FLT3, respectively). FN-1501 also has anticancer activity.
CAS:
1429515-59-2
Formula:
C22H25N9O
Molecular Weight:
431.504
Pathway:
Angiogenesis; Tyrosine Kinase/Adaptors; Cell Cycle/Checkpoint
Purity:
0.9635
SMILES:
CN1CCN(Cc2ccc(NC(=O)c3n[nH]cc3Nc3ncnc4[nH]ccc34)cc2)CC1
Target:
FLT; CDK

References

1. Wang Y, et al. Discovery of 4-((7H-Pyrrolo[2,3-d]pyrimidin-4-yl)amino)-N-(4-((4-methylpiperazin-1-yl)methyl)phenyl)-1H-pyrazole-3-carboxamide (FN-1501), an FLT3- and CDK-Kinase Inhibitor with Potentially High Efficiency against Acute Myelocytic Leukemia. J Med Chem. 2018 Feb 22;61(4):1499-1518.