TargetMol

Estetrol

Product Code:
 
TAR-T15248
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T15248-1mg1mg£173.00
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TAR-T15248-5mg5mg£332.00
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TAR-T15248-1mL1 mL * 10 mM (in DMSO)£426.00
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TAR-T15248-10mg10mg£461.00
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TAR-T15248-25mg25mg£695.00
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TAR-T15248-50mg50mg£922.00
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Quantity:
TAR-T15248-100mg100mg£1,219.00
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This product comes from: United States.
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Further Information

Bioactivity:
Estetrol is a selective nuclear estrogen receptor modulator. Estetrol also is a natural estrogen synthesized exclusively during pregnancy by the human fetal liver. Estetrol exerts estrogenic actions on the endometrium or the central nervous system but presents antagonistic effects on the breast.
CAS:
15183-37-6
Formula:
C18H24O4
Molecular Weight:
304.386
Pathway:
Endocrinology/Hormones|Metabolism
Purity:
0.98
SMILES:
[H][C@@]12[C@@H](O)[C@@H](O)[C@H](O)[C@@]1(C)CC[C@]1([H])c3ccc(O)cc3CC[C@@]21[H]
Target:
Endogenous Metabolite|Estrogen Receptor/ERR

References

1. Val?ra MC, et al. Effect of estetrol, a selective nuclear estrogen receptor modulator, in mouse models of arterial and venous thrombosis. Mol Cell Endocrinol. 2018 Dec 5;477:132-139. 2. Montt-Guevara MM, et al. Estetrol Modulates Endothelial Nitric Oxide Synthesis in Human Endothelial Cells. Front Endocrinol (Lausanne). 2015 Jul 22;6:111.