TargetMol

ER-000444793

Product Code:
 
TAR-T15241
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T15241-1mg1mg£127.00
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TAR-T15241-5mg5mg£201.00
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TAR-T15241-1mL1 mL * 10 mM (in DMSO)£213.00
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TAR-T15241-10mg10mg£269.00
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TAR-T15241-25mg25mg£464.00
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TAR-T15241-50mg50mg£645.00
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TAR-T15241-100mg100mg£863.00
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TAR-T15241-500mg500mg£1,661.00
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This product comes from: United States.
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Further Information

Bioactivity:
ER-000444793 is a potent mitochondrial permeability transition pore (mPTP) opening inhibitor and it also inhibits mPTP (IC50: 2.8 μM).
CAS:
792957-74-5
Formula:
C23H18N2O2
Molecular Weight:
354.409
Pathway:
Metabolism;
Purity:
0.9955
SMILES:
O=C(Nc1ccccc1Cc1ccccc1)c1cc(=O)[nH]c2ccccc12
Target:
Mitochondrial Metabolism

References

1. Briston T, et al. Identification of ER-000444793, a Cyclophilin D-independent inhibitor of mitochondrial permeability transition, using a high-throughput screen in cryopreserved mitochondria. Sci Rep. 2016 Nov 25;6:37798.