TargetMol

CYM50260

Product Code:
 
TAR-T15031
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T15031-1mg1mg£164.00
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TAR-T15031-1mL1 mL * 10 mM (in DMSO)£293.00
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TAR-T15031-5mg5mg£359.00
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TAR-T15031-10mg10mg£502.00
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TAR-T15031-25mg25mg£768.00
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TAR-T15031-50mg50mg£1,026.00
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Quantity:
TAR-T15031-100mg100mg£1,348.00
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This product comes from: United States.
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Further Information

Bioactivity:
CYM50260 is an exquisitely agonist of sphingosine-1-phosphate 4 receptor (S1P4-R) (EC50: 45 nM). CYM50260 shows no activity against S1P1-R, S1P2-R, S1P3-R and S1P5-R.
CAS:
1355026-60-6
Formula:
C14H11Cl3FNO2
Molecular Weight:
350.6
Pathway:
; GPCR/G Protein
Purity:
0.98
SMILES:
FCc1ccc(OCCOc2ccc(Cl)cc2Cl)c(Cl)n1
Target:
LPL Receptor

References

1. Guerrero M, et al. Discovery, design and synthesis of novel potent and selective sphingosine-1-phosphate 4 receptor (S1P?-R) agonists. Bioorg Med Chem Lett. 2012 Jan 1;22(1):537-42. 2. Onuma T, et al. Sphingosine 1-phosphate (S1P) suppresses the collagen-induced activation of human platelets via S1P4 receptor. Thromb Res. 2017 Aug;156:91-100.