TargetMol

Caerulomycin A

Product Code:
 
TAR-T14854
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T14854-1mg1mg£301.00
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TAR-T14854-1mL1 mL * 10 mM (in DMSO)£626.00
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TAR-T14854-5mg5mg£626.00
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TAR-T14854-10mg10mg£862.00
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TAR-T14854-25mg25mg£1,267.00
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TAR-T14854-50mg50mg£1,645.00
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Quantity:
TAR-T14854-100mg100mg£2,231.00
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This product comes from: United States.
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Further Information

Bioactivity:
Caerulomycin A (Cerulomycin; Caerulomycin) is an antifungal compound. Which induces generation of T cells, enhances TGF-β-Smad3 protein signaling via suppressing interferon-γ-induced STAT1 signaling. Antifungal and antibiotic activity, and used in autoimmune diseases.
CAS:
21802-37-9
Formula:
C12H11N3O2
Molecular Weight:
229.239
Pathway:
Microbiology/Virology
Purity:
0.98
SMILES:
COc1cc(C=NO)nc(c1)-c1ccccn1
Target:
Antifungal

References

1. Gurram RK, et al. Caerulomycin A enhances transforming growth factor-? (TGF-?)-Smad3 protein signaling by suppressing interferon-? (IFN-?)-signal transducer and activator of transcription 1 (STAT1) protein signaling to expand regulatory T cells (Tregs). J Biol Chem. 2014 Jun 20;289(25):17515-28.