TargetMol

ALLO-2

Product Code:
 
TAR-T14188
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T14188-1mg1mg£164.00
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TAR-T14188-2mg2mg£205.00
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TAR-T14188-5mg5mg£303.00
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TAR-T14188-1mL1 mL * 10 mM (in DMSO)£326.00
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TAR-T14188-10mg10mg£436.00
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TAR-T14188-25mg25mg£675.00
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TAR-T14188-50mg50mg£922.00
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TAR-T14188-100mg100mg£1,219.00
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Quantity:
TAR-T14188-500mg500mg£2,368.00
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This product comes from: United States.
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Further Information

Bioactivity:
ALLO-2 is a Inhibitor of Drug-Resistant Smo Mutant.It inhibits Smo agonist Hh-Ag1.5-induced luciferase expression in TM3-Gli-Luc cells with IC50 of 6 nM.
CAS:
1357350-60-7
Formula:
C18H12F3N5O
Molecular Weight:
371.323
Pathway:
Stem Cells; GPCR/G Protein
Purity:
0.9867
SMILES:
FC(F)(F)Oc1ccc(cc1)-c1ccnc(Nc2ccc3[nH]ncc3c2)n1
Target:
Hedgehog/Smoothened; Smo

References

1. Tao H, et al. Small molecule antagonists in distinct binding modes inhibit drug-resistant mutant of smoothened. Chem Biol. 2011 Apr 22;18(4):432-7.