TargetMol

Adenosine A1 receptor activator T62

Product Code:
 
TAR-T14127
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T14127-1mg1mg£189.00
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TAR-T14127-5mg5mg£329.00
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TAR-T14127-10mg10mg£454.00
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TAR-T14127-1mL1 mL * 10 mM (in DMSO)£466.00
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TAR-T14127-25mg25mg£691.00
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TAR-T14127-50mg50mg£914.00
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TAR-T14127-100mg100mg£1,211.00
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TAR-T14127-500mg500mg£2,344.00
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Further Information

Bioactivity:
Adenosine A1 receptor activator T62 is an allosteric enhancer of adenosine A1 receptor, and it produces antinociception in animal models of acute pain and also reduces hypersensitivity in models of inflammatory and nerve-injury pain[1][2][3].
CAS:
40312-34-3
Formula:
C15H14ClNOS
Molecular Weight:
291.79
Pathway:
Neuroscience; GPCR/G Protein
Purity:
0.95
SMILES:
Nc1sc2CCCCc2c1C(=O)c1ccc(Cl)cc1
Target:
Adenosine Receptor

References

1. Obata H, et al. Spinal adenosine receptor activation reduces hypersensitivity after surgery by a different mechanism than after nerve injury. Anesthesiology. 2004 May;100(5):1258-62. 2. Li X, et al. Allosteric adenosine receptor modulation reduces hypersensitivity following peripheral inflammation by a central mechanism. J Pharmacol Exp Ther. 2003 Jun;305(3):950-5. 3. Soudijn W, et al. Allosteric modulation of G protein-coupled receptors: perspectives and recent developments. Drug Discov Today. 2004 Sep 1;9(17):752-8.