TargetMol

A-485

Product Code:
 
TAR-T14073
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T14073-1mg1mg£142.00
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TAR-T14073-5mg5mg£214.00
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TAR-T14073-10mg10mg£328.00
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TAR-T14073-50mg50mg£428.00
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TAR-T14073-100mg100mg£685.00
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This product comes from: United States.
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Further Information

Bioactivity:
A-485 is a potent and selective catalytic p300/CBP inhibitor(IC50s of 9.8 nM and 2.6 nM for p300 and CBP, respectively).
CAS:
1889279-16-6
Formula:
C25H24F4N4O5
Molecular Weight:
536.484
Pathway:
Chromatin/Epigenetic
Purity:
0.9832
SMILES:
CNC(=O)Nc1ccc2c(CC[C@@]22OC(=O)N(CC(=O)N(Cc3ccc(F)cc3)[C@@H](C)C(F)(F)F)C2=O)c1
Target:
Epigenetic Reader Domain; Histone Acetyltransferase

References

1. Lasko LM, et al. Discovery of a selective catalytic p300/CBP inhibitor that targets lineage-specific tumours. Nature. 2017 Oct 5;550(7674):128-132.