TargetMol

A-385358

Product Code:
 
TAR-T14071
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T14071-1mg1mg£145.00
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TAR-T14071-5mg5mg£227.00
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TAR-T14071-1mL1 mL * 10 mM (in DMSO)£298.00
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TAR-T14071-10mg10mg£308.00
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TAR-T14071-25mg25mg£482.00
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TAR-T14071-50mg50mg£667.00
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Quantity:
TAR-T14071-100mg100mg£914.00
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This product comes from: United States.
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Further Information

Bioactivity:
A-385358 is a selective Bcl-xL inhibitor with Kis of 0.80 nM for Bcl-xL and 67 nM for Bcl-2, respectively.
CAS:
406228-55-5
Formula:
C32H41N5O5S2
Molecular Weight:
639.83
Pathway:
Apoptosis
Purity:
0.974
SMILES:
CN(C)CC[C@H](CSc1ccccc1)Nc1ccc(cc1[N+]([O-])=O)S(=O)(=O)NC(=O)c1ccc(cc1)N1CCC(C)(C)CC1
Target:
BCL

References

1. Shoemaker AR, et al. A small-molecule inhibitor of Bcl-XL potentiates the activity of cytotoxic drugs in vitro and in vivo. Cancer Res. 2006 Sep 1;66(17):8731-9.