TargetMol

UNC6852

Product Code:
 
TAR-T13954
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T13954-1mg1mg£179.00
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TAR-T13954-5mg5mg£303.00
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TAR-T13954-1mL1 mL * 10 mM (in DMSO)£423.00
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TAR-T13954-10mg10mg£454.00
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TAR-T13954-25mg25mg£704.00
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TAR-T13954-50mg50mg£938.00
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Quantity:
TAR-T13954-100mg100mg£1,259.00
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This product comes from: United States.
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Further Information

Bioactivity:
UNC6852 contains an EED ligand (IC50 = 247 nM) and a von Hippel-Lindau ligand and is a selective polycomb repressive complex 2 (PRC2) degrader based on PROTAC.
CAS:
2688842-08-0
Formula:
C22H22N2O5
Molecular Weight:
394.42
Pathway:
Chromatin/Epigenetic
Purity:
0.98
SMILES:
CCc(n(Cc1ccccc1)c1ccc2)c(C(C(N)=O)=O)c1c2OCC(OC)=O
Target:
DNA Methyltransferase; Histone Methyltransferase

References

1. Potjewyd F, et al. Degradation of Polycomb Repressive Complex 2 with an EED-Targeted Bivalent Chemical Degrader. Cell Chem Biol. 2020 Jan 16;27(1):47-56.e15.