TargetMol

PROTAC SGK3 degrader-1

Product Code:
 
TAR-T13847
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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TAR-T13847-100mg100mgEnquire
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TAR-T13847-50mg50mgEnquire
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TAR-T13847-1mg1mg£457.00
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TAR-T13847-5mg5mg£857.00
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TAR-T13847-10mg10mg£1,315.00
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TAR-T13847-1mL1 mL * 10 mM (in DMSO)£2,096.00
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Further Information

Bioactivity:
PROTAC SGK3 degrader-1, is a potent SKG3 degrader based on PROTAC.
CAS:
2381320-35-8
Formula:
C57H73FN10O11S2
Molecular Weight:
1157.39
Purity:
0.98
SMILES:
Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)COCCOCCOCCCCCCN2CCO[C@@H](COc3nc(nc4[nH]ncc34)-c3ccc(NS(=O)(=O)c4cc(C)ccc4F)cc3)C2)C(C)(C)C)cc1

References

1. Tovell H, et al. Design and Characterization of SGK3-PROTAC1, an Isoform Specific SGK3 Kinase PROTAC Degrader. ACS Chem Biol. 2019 Sep 20;14(9):2024-2034.