TargetMol

MS1943

Product Code:
 
TAR-T13780
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T13780-1mg1mg£179.00
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TAR-T13780-5mg5mg£303.00
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TAR-T13780-1mL1 mL * 10 mM (in DMSO)£438.00
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TAR-T13780-10mg10mg£454.00
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TAR-T13780-25mg25mg£704.00
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TAR-T13780-50mg50mg£938.00
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TAR-T13780-100mg100mg£1,259.00
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Further Information

Bioactivity:
MS1943 is a orally bioavailable EZH2 selective degrader(IC50 of 120 nM).
CAS:
2225938-17-8
Formula:
C42H54N8O3
Molecular Weight:
718.947
Pathway:
Chromatin/Epigenetic; Apoptosis
Purity:
0.9826
SMILES:
CC(C)n1ncc2c(cc(cc12)-c1ccc(nc1)N1CCN(CCNC(=O)CC23C[C@H]4C[C@H](C[C@H](C4)C2)C3)CC1)C(=O)NCc1c(C)cc(C)[nH]c1=O
Target:
Apoptosis; Histone Methyltransferase

References

1. Ma A, et al. Discovery?of a?first-in-class?EZH2?selective?degrader.Nat Chem Biol.?2020 Feb;16(2):214-222.