TargetMol

AZ7550 hydrochloride

Product Code:
 
TAR-T13564L
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
❮❯

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CodeSizePrice
TAR-T13564L-1mg1mg£172.00
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TAR-T13564L-5mg5mg£277.00
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TAR-T13564L-10mg10mg£389.00
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TAR-T13564L-25mg25mg£603.00
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TAR-T13564L-50mg50mg£830.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
AZ7550 hydrochloride, an active metabolite of AZD9291, inhibits the activity of IGF1R (IC50: 1.6 μM).
CAS:
2309762-40-9
Formula:
C27H32ClN7O2
Molecular Weight:
522.04
Pathway:
Tyrosine Kinase/Adaptors; Angiogenesis; JAK/STAT signaling
Purity:
0.9707
SMILES:
C=CC(NC1=CC(NC2=NC=CC(C3=CN(C)C4=C3C=CC=C4)=N2)=C(OC)C=C1N(C)CCNC)=O.[H]Cl
Target:
EGFR; IGF-1R

References

1. Finlay MR, et al. Discovery of a potent and selective EGFR inhibitor (AZD9291) of both sensitizing and T790M resistance mutations that spares the wild type form of the receptor. J Med Chem. 2014 Oct 23;57(20):8249-67.