TargetMol

YM17E

Product Code:
 
TAR-T13373
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T13373-1mg1mg£115.00
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TAR-T13373-5mg5mg£160.00
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TAR-T13373-10mg10mg£197.00
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TAR-T13373-1mL1 mL * 10 mM (in DMSO)£198.00
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TAR-T13373-25mg25mg£280.00
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TAR-T13373-50mg50mg£381.00
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TAR-T13373-100mg100mg£532.00
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TAR-T13373-500mg500mg£1,083.00
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Further Information

Bioactivity:
YM17E is an inhibitor of ACAT with IC50 of 44 nM in rabbit liver microsomes in vitro.
CAS:
124900-72-7
Formula:
C40H56N6O2
Molecular Weight:
652.928
Pathway:
Metabolism; Neuroscience
Purity:
0.98
SMILES:
CN(C)c1ccc(NC(=O)N(Cc2cccc(CN(C3CCCCCC3)C(=O)Nc3ccc(cc3)N(C)C)c2)C2CCCCCC2)cc1
Target:
Acyltransferase; AChR

References

1. Kashiwa M, et al. Pharmacological properties of YM17E, an acyl-CoA:cholesterol acyltransferase inhibitor, and diarrheal effect in beagle dogs. Jpn J Pharmacol. 1997 Jan;73(1):41-50. 2. Uchida T, et al. Relationship between bioavailability and hypocholesterolemic activity of YM17E, an inhibitor of ACAT, in cholesterol-fed rats. Atherosclerosis. 1998 Mar;137(1):97-106.