TargetMol

XEN723

Product Code:
 
TAR-T13356
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T13356-1mg1mg£138.00
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TAR-T13356-5mg5mg£229.00
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TAR-T13356-1mL1 mL * 10 mM (in DMSO)£261.00
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TAR-T13356-10mg10mg£322.00
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TAR-T13356-25mg25mg£499.00
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TAR-T13356-50mg50mg£687.00
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TAR-T13356-100mg100mg£938.00
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TAR-T13356-500mg500mg£1,805.00
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Further Information

Bioactivity:
XEN723 is a potent thiazolylimidazolidinone Stearoyl-CoA Desaturase (SCD1) inhibitor(IC50s of 45 and 524 nM in mouse and HepG2 cell, respectively).
CAS:
1072803-08-7
Formula:
C21H20FN5O2S
Molecular Weight:
425.48
Pathway:
Metabolism
Purity:
0.9954
SMILES:
Cc1nc(sc1C(=O)NCc1cccnc1)N1CCN(Cc2ccc(F)cc2)C1=O
Target:
Dehydrogenase; Stearoyl-CoA Desaturase (SCD)

References

1. Sun S, et al. Systematic evaluation of amide bioisosteres leading to the discovery of novel and potent thiazolylimidazolidinone inhibitors of SCD1 for the treatment of metabolic diseases. Bioorg Med Chem Lett. 2014 Jan 15;24(2):520-5.