TargetMol

VU0650786

Product Code:
 
TAR-T13318
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T13318-1mg1mg£148.00
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TAR-T13318-5mg5mg£269.00
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TAR-T13318-1mL1 mL * 10 mM (in DMSO)£289.00
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TAR-T13318-10mg10mg£349.00
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TAR-T13318-25mg25mg£544.00
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TAR-T13318-50mg50mg£747.00
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Quantity:
TAR-T13318-100mg100mg£1,002.00
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This product comes from: United States.
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Further Information

Bioactivity:
VU0650786 is a selective and potent CNS penetrant negative allosteric modulator of metabotropic glutamate receptor subtype 3 (mGlu3 NAM) (IC50: 392 nM), with antidepressant and anxiolytic activity in rodents.
CAS:
1809085-30-0
Formula:
C18H15ClFN5O2
Molecular Weight:
387.8
Pathway:
Neuroscience
Purity:
0.9896
SMILES:
C[C@@H]1CN(C(=O)c2cc(COc3ccc(Cl)cn3)nn12)c1cccnc1F
Target:
GluR

References

1. Engers JL, et al. Discovery of a Selective and CNS Penetrant Negative Allosteric Modulator of Metabotropic Glutamate Receptor Subtype 3 with Antidepressant and Anxiolytic Activity in Rodents. J Med Chem. 2015 Sep 24;58(18):7485-500.