TargetMol

Unesbulin

Product Code:
 
TAR-T12575
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T12575-1mg1mg£142.00
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Quantity:
TAR-T12575-5mg5mg£229.00
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TAR-T12575-10mg10mg£322.00
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Quantity:
TAR-T12575-25mg25mg£535.00
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Quantity:
TAR-T12575-50mg50mg£740.00
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Quantity:
TAR-T12575-100mg100mg£994.00
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Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
PTC596 is an orally active and selective inhibitor of B-cell-specific Moloney murine leukemia virus integration site 1 (BMI-1).
CAS:
1610964-64-1
Formula:
C19H13F5N6
Molecular Weight:
420.347
Pathway:
Cell Cycle/Checkpoint; Apoptosis; DNA Damage/DNA Repair
Purity:
1
SMILES:
Cc1nc2ccc(F)cc2n1-c1nc(N)c(F)c(Nc2ccc(cc2)C(F)(F)F)n1
Target:
Apoptosis; BMI-1

References

1. Nishida Y, et al. The novel BMI-1 inhibitor PTC596 downregulates MCL-1 and induces p53-independent mitochondrial apoptosis in acute myeloid leukemia progenitor cells. Blood Cancer J. 2017 Feb 17;7(2):e527. 2. BMI1 inhibitor PTC596