TargetMol

NMS-859

Product Code:
 
TAR-T12236
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T12236-1mg1mg£201.00
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TAR-T12236-2mg2mg£253.00
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TAR-T12236-5mg5mg£349.00
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TAR-T12236-1mL1 mL * 10 mM (in DMSO)£377.00
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TAR-T12236-10mg10mg£470.00
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TAR-T12236-25mg25mg£707.00
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TAR-T12236-50mg50mg£978.00
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TAR-T12236-100mg100mg£1,291.00
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Quantity:
TAR-T12236-500mg500mg£2,456.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
NMS-859 is an effective and covalent inhibitor of valosin-containing protein (VCP)/p97 with IC50s of 0.37 μM and 0.36 μM for wild-type VCP in the presence of 60 μM and 1 mM ATP in cells, respectively.
CAS:
1449236-96-7
Formula:
C15H12ClN3O3S
Molecular Weight:
349.79
Purity:
0.9736
SMILES:
ClCC(=O)Nc1cccc(NC2=NS(=O)(=O)c3ccccc23)c1

References

1. Magnaghi P, et al. Covalent and allosteric inhibitors of the ATPase VCP/p97 induce cancer cell death. Nat Chem Biol. 2013 Sep;9(9):548-56.