TargetMol

Micrococcin P1

Product Code:
 
TAR-T12033
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T12033-1mg1mg£751.00
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This product comes from: United States.
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Further Information

Bioactivity:
Micrococcin P1 is a macrocyclic peptide antibiotic and is a potent hepatitis C virus (HCV) inhibitor(EC50 range of 0.1-0.5 μM)
CAS:
67401-56-3
Formula:
C48H49N13O9S6
Molecular Weight:
1144.36
Pathway:
Proteases/Proteasome; Microbiology/Virology
Purity:
0.98
SMILES:
[H][C@]1(NC(=O)c2csc(n2)-c2ccc(nc2-c2csc(n2)C(NC(=O)c2csc(n2)[C@@H](NC(=O)c2csc(n2)C(NC1=O)=CC)C(C)C)[C@@H](C)O)-c1nc(cs1)-c1nc(cs1)C(=O)NC(=C/C)C(=O)NC[C@@H](C)O)[C@@H](C)O
Target:
HCV Protease

References

1. Lee M, et al. Micrococcin P1, a naturally occurring macrocyclic peptide inhibiting hepatitis C virus entry in a pan-genotypic manner. Antiviral Res. 2016 Aug;132:287-95. 2. Akasapu S, et al. Total synthesis of micrococcin P1 and thiocillin I enabled by Mo(vi) catalyst. Chem Sci. 2018 Dec 3;10(7):1971-1975. 3. Carnio MC, et al. Pyridinyl polythiazole class peptide antibiotic micrococcin P1, secreted by foodborne Staphylococcus equorum WS2733, is biosynthesized nonribosomally. Eur J Biochem. 2001 Dec;268(24):6390-401.