TargetMol

LDC7559

Product Code:
 
TAR-T11828
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T11828-1mg1mg£128.00
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TAR-T11828-5mg5mg£229.00
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TAR-T11828-1mL1 mL * 10 mM (in DMSO)£252.00
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TAR-T11828-10mg10mg£334.00
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TAR-T11828-25mg25mg£519.00
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TAR-T11828-50mg50mg£703.00
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Quantity:
TAR-T11828-100mg100mg£970.00
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Further Information

Bioactivity:
LDC7559 inhibits gasdermin D (GSDMD) by blocking neutrophil extracellular trap (NET) at late stage.
CAS:
2407782-01-6
Formula:
C20H19N3O3
Molecular Weight:
349.38
Pathway:
Immunology/Inflammation; Apoptosis
Purity:
0.9947
SMILES:
O=C(NC1=CC=C2C(OCC3=CC(=NN3C2)C=4C=CC=CC4OC)=C1)C
Target:
Pyroptosis

References

1. Spel L, et al. Gasdermin D opens the way for NETs. Nat Rev Rheumatol. 2018 Dec;14(12):690-692. 2. Sollberger G, et al. Gasdermin D plays a vital role in the generation of neutrophil extracellular traps. Sci Immunol. 2018 Aug 24;3(26). pii: eaar6689.