TargetMol

Impurity F of Calcipotriol

Product Code:
 
TAR-T11646
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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Further Information

Bioactivity:
Impurity F of Calcipotriol is a impurity of Calcipotriol. Calcipotriol (MC 903; Calcipotriene) is a ligand of VDR-like receptors.
CAS:
112875-61-3
Formula:
C39H68O3Si2
Molecular Weight:
641.14
Purity:
0.98
SMILES:
[H][C@@]1(CC[C@@]2([H])C(CCC[C@]12C)=CC=C1C[C@H](C[C@H](O[Si](C)(C)C(C)(C)C)C1=C)O[Si](C)(C)C(C)(C)C)[C@H](C)C=C[C@@H](O)C1CC1

References

1. Binderup (1993) Comparison of calcipotriol with selected metabolites and analogues of vitamin D3: effects on cell growth regulation in vitro and calcium metabolism in vivo. Pharmacol.Toxicol. 72 240. 2. Knutson et al (1997) Pharmacokinetics and systemic effect on calcium homeostasis of 1a,24-dihydroxyvitamin D2 in rats. Biochem.Pharmacol. 53 829. 3. Wietrzyk et al (2007) Antitumor properties of diastereomeric and geometric analogs of vitamin D3. Anticancer Drugs 18 447.111 4. Lise Binderup,, Erik Bramm. Effects of a novel vitamin D analogue MC 903 on cell proliferation and differentiation in vitro and on calcium metabolism in vivo. Biochemical Pharmacology. Volume 37, Issue 5, 1 March 1988, Pages 889-895