TargetMol

NMI 8739

Product Code:
 
TAR-T11079
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T11079-1mg1mg£111.00
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TAR-T11079-5mg5mg£147.00
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TAR-T11079-1mL1 mL * 10 mM (in DMSO)£165.00
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TAR-T11079-10mg10mg£177.00
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TAR-T11079-25mg25mg£245.00
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TAR-T11079-50mg50mg£326.00
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Quantity:
TAR-T11079-100mg100mg£450.00
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Quantity:
TAR-T11079-500mg500mg£938.00
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This product comes from: United States.
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Further Information

Bioactivity:
NMI 8739 is an agonist of D2 autoreceptor. NMI 8739 reduces NO production and elicits concentration-dependent suppression of CCL-20, MCP-1 and IL-6 release.
CAS:
129024-87-9
Formula:
C30H41NO3
Molecular Weight:
463.662
Pathway:
GPCR/G Protein; Neuroscience
Purity:
0.9851
SMILES:
CCC=C/CC=C/CC=C/CC=C/CC=C/CC=C/CCC(=O)NCCc1ccc(O)c(O)c1
Target:
Dopamine Receptor

References

1. Shashoua VE, et al. N-docosahexaenoyl, 3 hydroxytyramine: a dopaminergic compound that penetrates the blood-brain barrier and suppresses appetite. Life Sci. 1996;58(16):1347-57. 2. Wang Y, et al. N-Docosahexaenoyl Dopamine, an Endocannabinoid-like Conjugate of Dopamine and the n-3 Fatty Acid Docosahexaenoic Acid, Attenuates Lipopolysaccharide-Induced Activation of Microglia and Macrophages via COX-2. ACS Chem Neurosci. 2017 Mar 15;8(3):548-557. 3. Gill Higgins. New drugs signal rapid growth of anti-obesity drug market. RESEARCH & DEVELOPMENT. 2 Nov 11K16 No. 1061