TargetMol

hDHODH-IN-5

Product Code:
 
TAR-T11029
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T11029-1mg1mg£132.00
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TAR-T11029-5mg5mg£206.00
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TAR-T11029-1mL1 mL * 10 mM (in DMSO)£219.00
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TAR-T11029-10mg10mg£268.00
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TAR-T11029-25mg25mg£389.00
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TAR-T11029-50mg50mg£544.00
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TAR-T11029-100mg100mg£744.00
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Further Information

Bioactivity:
hDHODH-IN-5 is an inhibitor of human dihydroorotate dehydrogenase (hDHODH, IC50 = 0.91 μM).
CAS:
2029049-77-0
Formula:
C21H21F3N2O2
Molecular Weight:
390.406
Pathway:
Metabolism
Purity:
0.987
SMILES:
FC(F)(F)c1ccc(cc1)C(=O)NCCC(=O)N[C@@H]1CCCc2ccccc12
Target:
Dehydrogenase

References

1. Lewis TA, et al. Development?of?ML390: A?Human?DHODH?Inhibitor?That?Induces?Differentiation?in?Acute?Myeloid?Leukemia. ACS Med Chem Lett.?2016 Sep 28;7(12):1112-1117.