ProSci

IFI16 (CT) Peptide

Product Code:
 
PSI-9641P
Product Group:
 
Peptides
Supplier:
 
ProSci
Regulatory Status:
 
RUO
Application:
 
Blocking
Shipping:
 
Blue Ice
Storage:
 
Store ULBP1 peptide at -20˚C, stable for one year.
 

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CodeSizePrice
PSI-9641P-0.05mg0.05mg£166.00
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Further Information

Additional Names:
IFI16 Antibody: Gamma-interferon-inducible protein 16, Ifi-16, Interferon-inducible myeloid differentiation transcriptional activator, IFNGIP1
Application Note:
IFI16 (CT) Peptide is used for blocking the activity of IFI16 (CT) Antibody.
Background:
IFI16 Antibody: IFI16 inhibits DNA repair that potentiates type-I interferon-induced antitumor effects in triple negative breast cancer. Increased expression of IFI16 predicts adverse prognosis in multiple myeloma. IFI16 isoforms with cytoplasmic and nuclear locations play differential roles in recognizing invaded DNA viruses. IFI16 directly senses viral RNA and enhances RIG-I transcription and activation to restrict influenza virus infection. Nuclear sensor IFI16 inhibits the function of Hepatitis B virus covalently closed circular DNA by integrating innate immune activation and epigenetic suppression.
Background References:
  • Ka et al. Cell Rep. 2021; 37(12):110138
  • Huang et al. Pharmacogenomics J. 2021; 21(4):520-532
  • Li et al. J Immunol. 2021; 207(11):2699-2709
  • Jiang et al. Nat Microbiol. 2021; 6(7):932-945
  • Yang et al. Hepatology 2020; 71(4):1154-1169
Buffer:
PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide
Concentration:
200 ug/mL
NCBI Gene ID #:
3428
NCBI Official Name:
interferon gamma inducible protein 16
NCBI Official Symbol:
IFI16
NCBI Organism:
Homo sapiens
Peptide aa Location:
16 amino acids near the carboxyl terminus of human IFI16.
Physical State:
Liquid
Protein Accession #:
Q16666.3
Protein GI Number:
118572657
Swissprot #:
Q16666
User Note:
Optimal dilutions for each application to be determined by the researcher.

Documents