NSJ Bioreagents

SMURF2 Antibody

Product Code:
 
NSJ-RQ5537
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
 
After reconstitution, the SMURF2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
1 / 2
Western blot testing of 1) rat testis, 2) rat pancreas, 3) rat stomach, 4) mouse testis and 5) mouse pancreas lysate with SMURF2 antibody. Predicted molecular weight ~86 kDa.
2 / 2
Western blot testing of human 1) A549 and 2) HepG2 lysate with SMURF2 antibody. Predicted molecular weight ~86 kDa.
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Western blot testing of 1) rat testis, 2) rat pancreas, 3) rat stomach, 4) mouse testis and 5) mouse pancreas lysate with SMURF2 antibody. Predicted molecular weight ~86 kDa.
Western blot testing of human 1) A549 and 2) HepG2 lysate with SMURF2 antibody. Predicted molecular weight ~86 kDa.

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CodeSizePrice
NSJ-RQ5537-100ug100 ug£535.00
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Further Information

Application Details :
Western blot: 0.25-0.5ug/ml,Direct ELISA: 0.1-0.5ug/ml
Application Note:
Optimal dilution of the SMURF2 antibody should be determined by the researcher.
Buffer:
Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide
Description:
E3 ubiquitin-protein ligase SMURF2 is an enzyme that in humans is encoded by the SMURF2 gene. The SMURF2 gene is mapped to chromosome 17q22-q23 based on sequence similarity between the SMURF2 sequence and a genomic contig. SMURF2 is a HECT domain E3 ubiquitin ligase involved in degradation of SMADs, TGF-beta receptor (TGFBR), and other substrates. It also functions in regulation of neuronal and planar cell polarity, induction of senescence, and tumor suppression.
Format :
Antigen affinity purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
A human recombinant protein (amino acids W303-Q387) was used as the immunogen for the SMURF2 antibody.
Limitation:
This SMURF2 antibody is available for research use only.
Purity:
Affinity purified
Species Reactivity :
Human, Mouse, Rat
Uniprot #:
Q9HAU4