NSJ Bioreagents

SMOX Antibody

Product Code:
 
NSJ-RQ5536
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
 
After reconstitution, the SMOX antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
1 / 2
Western blot testing of human 1) A549, 2) PC-3 and 3) U-2 OS cell lysate with SMOX antibody. Predicted molecular weight ~62 kDa.
2 / 2
Western blot testing of 1) rat brain, 2) rat heart, 3) mouse brain and 4) mouse NIH3T3 cell lysate with SMOX antibody. Predicted molecular weight ~62 kDa.

Western blot testing of human 1) A549, 2) PC-3 and 3) U-2 OS cell lysate with SMOX antibody. Predicted molecular weight ~62 kDa.
Western blot testing of 1) rat brain, 2) rat heart, 3) mouse brain and 4) mouse NIH3T3 cell lysate with SMOX antibody. Predicted molecular weight ~62 kDa.

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CodeSizePrice
NSJ-RQ5536-100ug100 ug£535.00
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This product comes from: United States.
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Further Information

Application Details :
Western blot: 0.25-0.5ug/ml,Direct ELISA: 0.1-0.5ug/ml
Application Note:
Optimal dilution of the SMOX antibody should be determined by the researcher.
Buffer:
Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide
Description:
Spermine oxidase is an enzyme that in humans is encoded by the SMOX gene. It is mapped to 2; 2 F1. Polyamines are ubiquitous polycationic alkylamines which include spermine, spermidine, putrescine, and agmatine. These molecules participate in a broad range of cellular functions which include cell cycle modulation, scavenging reactive oxygen species, and the control of gene expression. These molecules also play important roles in neurotransmission through their regulation of cell-surface receptor activity, involvement in intracellular signalling pathways, and their putative roles as neurotransmitters. This gene encodes an FAD-containing enzyme that catalyzes the oxidation of spermine to spermadine and secondarily produces hydrogen peroxide. Multiple transcript variants encoding different isoenzymes have been identified for this gene, some of which have failed to demonstrate significant oxidase activity on natural polyamine substrates. The characterized isoenzymes have distinctive biochemical characteristics and substrate specificities, suggesting the existence of additional levels of complexity in polyamine catabolism.
Format :
Antigen affinity purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
A mouse recombinant protein (amino acids A40-P555) was used as the immunogen for the SMOX antibody.
Limitation:
This SMOX antibody is available for research use only.
Purity:
Affinity purified
Species Reactivity :
Human, Mouse, Rat
Uniprot #:
Q99K82