Dystrophin Antibody / DMD

Western blot: 1:500-1:2000

Optimal dilution of the Dystrophin antibody should be determined by the researcher.

The DMD gene spans a genomic range of greater than 2 Mb and encodes a large protein containing an N-terminal actin-binding domain and multiple spectrin repeats. The encoded protein forms a component of the dystrophin-glycoprotein complex (DGC), which bridges the inner cytoskeleton and the extracellular matrix. Deletions, duplications, and point mutations at this gene locus may cause Duchenne muscular dystrophy (DMD), Becker muscular dystrophy (BMD), or cardiomyopathy. Alternative promoter usage and alternative splicing result in numerous distinct transcript variants and protein isoforms for this gene. [RefSeq]

Purified

Antibody in PBS with 0.02% sodium azide and 50% glycerol

A synthetic peptide specific to human Dystrophin / DMD was used as the immunogen for the Dystrophin antibody.

This Dystrophin antibody is available for research use only.

Affinity purified

Human

P11532