RevMab Biosciences

anti-Annexin A1 (human) Rabbit Monoclonal (RM424)

Product Code:
 
REV-31-1311-00
Product Group:
 
Primary Antibodies
Supplier:
 
RevMab Biosciences
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit IgG
Antibody Clonality:
 
Recombinant Antibody
Antibody Clone:
 
RM424
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Shipping:
 
BLUE ICE
Storage:
 
Long Term: -20°C
1 / 1
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REV-31-1311-00-R100100 ul£455.00
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This product comes from: Switzerland.
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Further Information

Alternate Names/Synonyms:
Lipocortin-1; p35; Annexin-1; Calpactin-2; Calpactin II; Lipocortin I; Chromobindin-9; Phospholipase A2 Inhibitory Protein
Concentration:
N/A
EClass:
32160000
Form (Short):
liquid
Formulation:
Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide.
Handling Advice:
Avoid freeze/thaw cycles.
Immunogen:
A peptide corresponding to the N-terminus of human Annexin A1.
Long Description:
Recombinant Antibody. This antibody RM424 reacts to human Annexin A1. Application: IHC, WB . Source: Rabbit. Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide. The annexin superfamily consists of 13 calcium or calcium and phospholipid binding proteins with high biological and structural homology. Annexin-1 (ANXA1) is the first characterized member of the annexin family of proteins and is able to bind to cellular membranes in a calcium-dependent manner, promoting membrane fusion and endocytosis. Loss of function or expression of this gene has been detected in multiple tumors. Annexin A1 has anti-inflammatory properties and inhibits phospholipase A2 activity, can accumulate on internalized vesicles after EGF-stimulated endocytosis and may be required for a late stage in inward vesiculation. Annexin A1 has also been identified as one of the 'eat-me' signals on apoptotic cells that are to be recognized and ingested by phagocytes. Annexin A1, as an endogenous anti-inflammatory mediator, has roles in many diverse cellular functions, such as membrane aggregation, inflammation, phagocytosis, proliferation, apoptosis and tumorigenesis and cancer development.
NCBI, Uniprot Number:
P04083
Package Type:
Vial
Product Description:
The annexin superfamily consists of 13 calcium or calcium and phospholipid binding proteins with high biological and structural homology. Annexin-1 (ANXA1) is the first characterized member of the annexin family of proteins and is able to bind to cellular membranes in a calcium-dependent manner, promoting membrane fusion and endocytosis. Loss of function or expression of this gene has been detected in multiple tumors. Annexin A1 has anti-inflammatory properties and inhibits phospholipase A2 activity, can accumulate on internalized vesicles after EGF-stimulated endocytosis and may be required for a late stage in inward vesiculation. Annexin A1 has also been identified as one of the 'eat-me' signals on apoptotic cells that are to be recognized and ingested by phagocytes. Annexin A1, as an endogenous anti-inflammatory mediator, has roles in many diverse cellular functions, such as membrane aggregation, inflammation, phagocytosis, proliferation, apoptosis and tumorigenesis and cancer development.
Purity:
Protein A purified.
Source / Host:
Rabbit
Specificity:
RM424 reacts to human Annexin A1.
Transportation:
Non-hazardous
UNSPSC Category:
Primary Antibodies
UNSPSC Number:
12352203
Use & Stability:
Stable for at least 1 year after receipt when stored at -20°C.