NSJ Bioreagents

HES1 Antibody

Product Code:
 
NSJ-F53422
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Mouse
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
 
Aliquot the HES1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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Western blot testing of HES1 antibody at 1:2000 dilution + mouse brain lysate; Predicted molecular weight: 30-35 kDa.
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Western blot testing of HES1 antibody at 1:2000 dilution + mouse brain lysate; Predicted molecular weight: 30-35 kDa.

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CodeSizePrice
NSJ-F53422-0.08ML0.08 ml£260.00
Quantity:
NSJ-F53422-0.4ML0.4 ml£502.00
Quantity:
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Further Information

Application Details :
Western blot: 1:2000
Application Note:
Titration of the HES1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
Transcriptional repressor of genes that require a bHLH protein for their transcription. May act as a negative regulator of myogenesis by inhibiting the functions of MYOD1 and ASH1. Binds DNA on N-box motifs: 5'-CACNAG-3' with high affinity and on E-box motifs: 5'-CANNTG-3' with low affinity (By similarity). May play a role in a functional FA core complex response to DNA cross-link damage, being required for the stability and nuclear localization of FA core complex proteins, as well as for FANCD2 monoubiquitination in response to DNA damage.
Format :
Antigen affinity purified
Formulation :
In 1X PBS, pH 7.4, with 0.09% sodium azide
Immunogen:
This HES1 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 203-236 amino acids from the C-terminal region of human HES1.
Limitation:
This HES1 antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Mouse
Uniprot #:
Q14469