NSJ Bioreagents

HDAC6 Antibody

Product Code:
 
NSJ-F41165
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Storage:
 
Aliquot the HDAC6 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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IHC analysis of FFPE human hepatocarcinoma stained with HDAC6 antibody~
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HDAC6 antibody used in western blot to detect HDAC6 in mouse kidney tissue lysate. Predicted molecular weight ~131 kDa.
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IHC analysis of FFPE human hepatocarcinoma stained with HDAC6 antibody~
HDAC6 antibody used in western blot to detect HDAC6 in mouse kidney tissue lysate. Predicted molecular weight ~131 kDa.

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CodeSizePrice
NSJ-F41165-0.08ML0.08 ml£260.00
Quantity:
NSJ-F41165-0.4ML0.4 ml£502.00
Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Application Details :
IHC (Paraffin): 1:10-1:50,Western blot: 1:1000
Application Note:
Titration of the HDAC6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
HDAC6 (histone deacetylase 6) is responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. HDAC6 plays a central role in microtubule-dependent cell motility via deacetylation of tubulin, and has been shown to interact with HDAC11, SIRT2, and F-actin. HDAC6 is ubiquitinated, but its polyubiquitination however does not lead to degradation. HDAC is also a potential target of sumoylation.
Format :
Purified
Formulation :
In 1X PBS, pH 7.4, with 0.09% sodium azide
Immunogen:
A portion of amino acids 1182-1215 from the human protein was used as the immunogen for this HDAC6 antibody.
Limitation:
This HDAC6 antibody is available for research use only.
Purity:
Purified
Species Reactivity :
Human, Mouse
Uniprot #:
Q9UBN7