NSJ Bioreagents

Runx1 Antibody

Product Code:
 
NSJ-F53294
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
 
Aliquot the Runx1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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Western blot testing of Runx1 antibody at 1:2000 dilution. Lane 1: Jurkat lysate; 2: NIH3T3 lysate; 3: mouse thymus lysate; Predicted molecular weight: 49 kDa.
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Western blot testing of Runx1 antibody at 1:2000 dilution. Lane 1: Jurkat lysate; 2: NIH3T3 lysate; 3: mouse thymus lysate; Predicted molecular weight: 49 kDa.

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CodeSizePrice
NSJ-F53294-0.08ML0.08 ml£260.00
Quantity:
NSJ-F53294-0.4ML0.4 ml£502.00
Quantity:
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This product comes from: United States.
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Further Information

Application Details :
Western blot: 1:2000
Application Note:
Titration of the Runx1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, LCK, IL-3 and GM-CSF promoters. Essential for the development of normal hematopoiesis. Isoform 4 shows higher binding activities for target genes and binds TCR-beta-E2 and RAG-1 target site with threefold higher affinity than other isoforms. It is less effective in the context of neutrophil terminal differentiation. Acts synergistically with ELF4 to transactivate the IL-3 promoter and with ELF2 to transactivate the BLK promoter. Inhibits KAT6B- dependent transcriptional activation (By similarity).
Format :
Antigen affinity purified
Formulation :
In 1X PBS, pH 7.4, with 0.09% sodium azide
Immunogen:
This Runx1 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 426-459 amino acids from the C-terminal region of mouse Runx1.
Limitation:
This Runx1 antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Human, Mouse
Uniprot #:
Q03347