NSJ Bioreagents

CD163 Antibody

Product Code:
 
NSJ-F50316
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Storage:
 
Aliquot the CD163 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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Western blot analysis of CD163 antibody and K562 lysate~
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IHC analysis of FFPE human hepatocarcinoma with CD163 antibody
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Western blot analysis of CD163 antibody and K562 lysate~
IHC analysis of FFPE human hepatocarcinoma with CD163 antibody

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CodeSizePrice
NSJ-F50316-0.08ML0.08 ml£260.00
Quantity:
NSJ-F50316-0.4ML0.4 ml£502.00
Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Application Details :
Western blot: 1:1000,IHC (Paraffin): 1:10-1:50
Application Note:
Titration of the CD163 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
CD163 is an acute phase-regulated receptor involved in clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages and may thereby protect tissues from free hemoglobin-mediated oxidative damage. The protein may play a role in the uptake and recycling of iron, via endocytosis of hemoglobin/haptoglobin and subsequent breakdown of heme. It binds hemoglobin/haptoglobin complexes in a calcium-dependent and pH-dependent manner. And it exhibits a higher affinity for complexes of hemoglobin and multimeric haptoglobin of HP*1F phenotype than for complexes of hemoglobin and dimeric haptoglobin of HP*1S phenotype. It also induces a cascade of intracellular signals that involves tyrosine kinase-dependent calcium mobilization, inositol triphosphate production and secretion of IL6 and CSF1.
Format :
Purified
Formulation :
In 1X PBS, pH 7.4, with 0.09% sodium azide
Immunogen:
A portion of amino acids 245-274 from the human protein was used as the immunogen for this CD163 antibody.
Limitation:
This CD163 antibody is available for research use only.
Purity:
Purified
Species Reactivity :
Human
Uniprot #:
Q86VB7