NSJ Bioreagents

MUC1 Antibody / Mucin-1

Product Code:
 
NSJ-V9048
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Mouse
Antibody Isotype:
 
Mouse IgG2a, lambda
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
SPM533
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Immunohistochemistry- Paraffin Embedded (IHC-P)
Storage:
 
Store the Mucin-1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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IHC: Formalin-fixed, paraffin-embedded human breast carcinoma stained with Mucin-1 antibody (clone SPM533).
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IHC: Formalin-fixed, paraffin-embedded human breast carcinoma stained with Mucin-1 antibody (clone SPM533).

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CodeSizePrice
NSJ-V9048-20UG20 ug£264.00
Quantity:
NSJ-V9048-100UG100 ug£534.00
Quantity:
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Further Information

Application Details :
Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT
Application Note:
Optimal dilution of the antibody should be determined by the researcher.
Description:
Mucin-1 is a 265-400kDa glycoprotein. This protein is proteolytically cleaved into alpha and beta subunits that form a heterodimeric complex. The N-terminal alpha subunit and the C-terminal beta subunit. . The alpha subunit has cell adhesive properties. It can act both as an adhesion and an anti-adhesion protein. MUC1 may provide a protective layer on epithelial cells against bacterial and enzyme attack. The beta subunit contains a C-terminal domain, which is involved in cell signaling, through phosphorylations and protein-protein interactions.
Format :
Purified
Formulation :
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Immunogen:
Delipidated extract of human milk fat globule membranes was used as the immunogen for this Mucin-1 antibody.
Limitation:
This Mucin-1 antibody is available for research use only.
Localization:
Cytoplasmic & cell surface
Purity:
Protein G affinity chromatography
Species Reactivity :
Human
Uniprot #:
P15941