NSJ Bioreagents

PD-L1 Antibody / B7-H1 / CD274

Product Code:
 
NSJ-V8067
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Mouse
Antibody Isotype:
 
Rabbit IgG, kappa
Antibody Clonality:
 
Recombinant Antibody
Antibody Clone:
 
PDL1/4451R
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Immunohistochemistry- Paraffin Embedded (IHC-P)
Storage:
 
Store the recombinant PD-L1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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IHC testing of FFPE lung SCC with recombinant PD-L1 antibody (clone PDL1/4451R). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 10-20 min followed by cooling at RT for 20 min.~
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IHC testing of FFPE lung SCC with recombinan
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IHC testing of FFPE lung SCC with recombinant PD-L1 antibody (clone PDL1/4451R). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 10-20 min followed by cooling at RT for 20 min.~
IHC testing of FFPE lung SCC with recombinan

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CodeSizePrice
NSJ-V8067-20UG20 ug£264.00
Quantity:
NSJ-V8067-100UG100 ug£534.00
Quantity:
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Further Information

Application Details :
Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT
Application Note:
Optimal dilution of the antibody should be determined by the researcher.
Description:
PD-L1 is a checkpoint regulator in immune cells, it is expressed on immune or non-hematopoietic cells. Expression of the protein is seen during pregnancy where it has a role in suppressing the immune system. PD-L1 induces an inhibitory signal in activated T-cells and promotes T-cell apoptosis. It is overexpressed in a number of different cancers where it is believed to play a significant role in the cancer’s ability to evade the immune system.
Format :
Purified
Formulation :
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Immunogen:
A portion of amino acids 39-191 from the human protein was used as the immunogen for this recombinant PD-L1 antibody.
Limitation:
This recombinant PD-L1 antibody is available for research use only.
Localization:
Cell surface, cytoplasm
Purity:
Protein A affinity chromatography
Species Reactivity :
Human
Uniprot #:
Q9NZQ7