Omeprazole sulfide
Product Code:
CDX-O0041
CDX-O0041
Regulatory Status:
RUO
RUO
Shipping:
AMBIENT
AMBIENT
Storage:
Short Term: +4°C, Long Term: -20°C
Short Term: +4°C, Long Term: -20°C
No additional charges, what you see is what you pay! *
Code | Size | Price |
---|
CDX-O0041-M025 | 25 mg | £48.00 |
Quantity:
CDX-O0041-M250 | 250 mg | £132.00 |
Quantity:
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* Rare exceptions are clearly labelled (only 0.14% of items!).
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This product comes from: Switzerland.
Typical lead time: 7-10 working days.
Contact us for more accurate information.
Typical lead time: 7-10 working days.
Contact us for more accurate information.
- Further Information
- Documents
- References
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Further Information
Alternate Names/Synonyms:
Omeprazole impurity C (PhEur); Pyrmetazol; Ufiprazole
Appearance:
White to off-white powder.
CAS:
73590-85-9
EClass:
32160000
Form (Short):
liquid
GHS Symbol:
GHS07
Handling Advice:
Protect from light and moisture.
Hazards:
H315-H319-H335
InChi:
InChI=1S/C17H19N3O2S/c1-10-8-18-15(11(2)16(10)22-4)9-23-17-19-13-6-5-12(21-3)7-14(13)20-17/h5-8H,9H2,1-4H3,(H,19,20)
InChiKey:
XURCIPRUUASYLR-UHFFFAOYSA-N
Long Description:
Chemical. CAS: 73590-85-9. Formula: C17H19N3O2S. MW: 329.42. Omeprazole sulfide is an aryl hydrocarbon receptor (AhR) antagonist. Omeprazole sulfide is an intermediate used in the production of the gastric proton pump inhibitors, omeprazole and esomeprazole. Omeprazole sulfide is also a degradation product (Omeprazole Impurity C) of Omperazole, and it is reported to be a direct-acting inhibitor of cytochrome P450 2C19 in pooled human liver microsomes. Omeprazole is a selective and irreversible proton pump inhibitor. It suppresses stomach acid secretion by specific inhibition of the H+/K+-ATPase system found at the secretory surface of gastric parietal cells. Because this enzyme system is regarded as the acid (proton, or H+) pump within the gastric mucosa, omeprazole inhibits the final step of acid production. Omeprazole sulfide can be usd as reference material.
MDL:
MFCD00869021
Molecular Formula:
C17H19N3O2S
Molecular Weight:
329.42
Package Type:
Vial
Precautions:
P261-P305 + P351 + P338
Product Description:
Omeprazole sulfide is an aryl hydrocarbon receptor (AhR) antagonist. Omeprazole sulfide is an intermediate used in the production of the gastric proton pump inhibitors, omeprazole and esomeprazole. Omeprazole sulfide is also a degradation product (Omeprazole Impurity C) of Omperazole, and it is reported to be a direct-acting inhibitor of cytochrome P450 2C19 in pooled human liver microsomes. Omeprazole is a selective and irreversible proton pump inhibitor. It suppresses stomach acid secretion by specific inhibition of the H+/K+-ATPase system found at the secretory surface of gastric parietal cells. Because this enzyme system is regarded as the acid (proton, or H+) pump within the gastric mucosa, omeprazole inhibits the final step of acid production. Omeprazole sulfide can be usd as reference material.
Purity:
>97% (NMR)
Signal word:
Warning
SMILES:
CC(C(OC)=C(C)C=N1)=C1CSC2=NC3=CC(OC)=CC=C3N2
Solubility Chemicals:
Soluble in DMSO (10mg/ml), DMF (10mg/ml) or ethanol (10mg/ml).
Transportation:
Non-hazardous
UNSPSC Category:
Biochemical Reagents
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.
Documents
References
(1) S. Gerbal-Chaloin, et al.; Cell Signal. 18, 740 (2006) | (2) B.W. Ogilvie, e al.; Drug Metab. Dispos. 39, 2020 (2011) | (3) L. Olbe, et al.; Nat. Rev. Drug Discovery 2, 132 (2003) (Review)