ProSci

SARS-CoV-2 (COVID-19) S Protein RBD-SD1 Recombinant Protein

Product Code:
 
PSI-92-737
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Host Type:
 
Human
Regulatory Status:
 
RUO
Shipping:
 
blue ice or RT
Storage:
 
Reconstituted protein solution should be store below -20˚C.
 

No additional charges, what you see is what you pay! *

CodeSizePrice
PSI-92-737-0.02mg0.02mg£560.00
Quantity:
Prices exclude any Taxes / VAT
Stay in control of your spending. These prices have no additional charges, not even shipping!
* Rare exceptions are clearly labelled (only 0.14% of items!).
Multibuy discounts available! Contact us to find what you can save.
This product comes from: United States.
Typical lead time: 14-21 working days.
Contact us for more accurate information.
  • Further Information
  • Documents
  • Show All

Further Information

Additional Names:
2019-nCov RBD Protein; 2019-nCoV Spike RBD Protein
Application Note:
This recombinant protein can be used for biological assays. For research use only.
Background:
Protein S (PROS1) is glycoprotein and expressed in many cell types supporting its reported involvement in multiple biological processes that include coagulation, apoptosis, cancer development and progression, and the innate immune response. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2, DPP4, CEACAM etc.. The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process. Most notable is severe acute respiratory syndrome (SARS). The severe acute respiratory syndrome-coronavirus (SARS-CoV) spike (S) glycoprotein alone can mediate the membrane fusion required for virus entry and cell fusion. It is also a major immunogen and a target for entry inhibitors. It's been reported that 2019-nCoV can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
Buffer:
Supplied as a 0.2 uM filtered solution of PBS, PH7.4.
Fusion Tag:
C-Avi-6His tag
NCBI Gene ID #:
43740568
NCBI Official Name:
Surface glycoprotein
NCBI Official Symbol:
S
NCBI Organism:
Severe acute respiratory syndrome coronavirus 2
Physical State:
Liquid
Predicted Molecular Weight:
33.2kDa, 38-35kDa
Protein Accession #:
QHD43416.1
Purity:
Greater than 95% as determined by reducing SDS-PAGE.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
Mammalian Cells
Swissprot #:
QHD43416.1

Documents