ProSci

Gemtuzumab (CD33) Antibody, Monoclonal

Product Code:
 
PSI-10-081
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Antibody Isotype:
 
IgG4-kappa
Antibody Clonality:
 
Recombinant Antibody
Regulatory Status:
 
RUO
Shipping:
 
blue ice
Storage:
 
Store at -80˚C
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PSI-10-081-0.1mg0.1mg£657.00
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This product comes from: United States.
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Further Information

Additional Names:
CDP-771,CMA-676 (ADC),WAY-CMA-676,gemtuzumab ozogamicin,hP67.6 (naked),hP67.6-calicheamicin (ADC), CD33, CD33
Background:
Gemtuzumab ozogamicin is a recombinant humanized IgG4 kappa antibody which is conjugated with calicheamicin derivative,a cytotoxic antitumor antibiotic isolated from fermentation of Micromonospora echinospora ssp.calichensis.Gemtuzumab ozogamicin has approximately 50% of the antibody loaded with 4-6 moles calicheamicin per mole of antibody?Label.The antibody is specifically directed against the CD33 antigen present on leukemic myeloblasts in most patients with acute myeloid leukemia (AML).By binding to the CD33 antigen on tumors,the cytotoxic agent blocks the growth of cancerous cells and causes cell death.
Buffer:
PBS buffer pH7.5
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Humanized / CD33 [Homo sapiens]
NCBI Organism:
homo sapiens
Purification:
>95%
Research Area:
Drug Analogues
Source:
CHO cells
Swissprot #:
P20138
User NOte:
Optimal dilutions for each application to be determined by the researcher.