ProSci

Ebselen

Product Code:
 
PSI-10-023
Product Group:
 
Inhibitors and Activators
Supplier:
 
ProSci
Regulatory Status:
 
RUO
Shipping:
 
blue ice
Storage:
 
Short Term Storage:+4C. Long Term Storage: -20C. Handling Advice: Protect from light. Use/Stability: Stable for at least 2 years after receipt when stored at -20C.
 

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PSI-10-023-25mg25mg£300.00
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Further Information

Additional Names:
2-Phenyl-12-benzisoselenazol-3-(2H)-one
Background:
Glutathione peroxidase mimetic [1, 4]. Peroxynitrite scavenger [4]. Anti-inflammatory [1, 5-7] Antioxidant [2, 3, 5]. Protein kinase C (PKC), NADPH, lipoxygenase, COX, NOS, H+-ATPase and NADPH oxidase inhibitor [6-9]. Antifungal [9]. Review [10]. Potent IDO-1 inhibitor with Ki 94nM [11]. Inhibitor of HIV-1 capsid C-terminal domain dimerization. Shown to potentially inhibit the 33.8-kDa Main Protease (Mpro)/3C-like Protease of SARS-CoV-2, consequently inhibiting viral transcription and replication and possibly inhibiting spread of COVID-19
CAS:
60940-34-3
Formula:
C13H9NOSe
Identity:
Determined by 1H-NMR.
InChi Key:
DYEFUKCXAQOFHX-UHFFFAOYSA-N
Merck Index:
3.004166667
Physical State:
Lyophilized
Predicted Molecular Weight:
274.2
Purity:
greater than or equal to 98% (HPLC)
Smiles:
O=C1N([Se]C2=C1C=CC=C2)C1=CC=CC=C1
Solubility:
Soluble in DMSO (25mg/ml), DMF (25mg/ml) or water (2mg/ml).
Soluble In Dmf, Ethanol, Dmso Or Aqueous Solvents (Pbs).:
Soluble in DMSO (25mg/ml), DMF (25mg/ml) or water (2mg/ml).

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