Further Information
Mast/stem cell growth factor receptor Kit, SCFR, Piebald trait protein, PBT, Proto-oncogene c-Kit, Tyrosine-protein kinase Kit, p145 c-kit, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog, CD117, KIT, SCFR
WB: 1:500 - 1:1000
IHC: 1:50 - 1:100
This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene.
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Recombinant fusion protein containing a sequence corresponding to amino acids 25-295 of human KIT (NP_000213.1).
3815
KIT proto-oncogene receptor tyrosine kinase
KIT
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
Observed: 125kDa
Affinity purification
Cancer, Cell Cycle, Chemokines & Cytokines, Growth Factors, Immunology, Neuroscience, Signal Transduction, Stem Cell
P10721
Optimal dilutions for each application to be determined by the researcher.