MAPKAPK3 Antibody, KO Validated
Antibody Clonality:
Polyclonal
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
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This product comes from:
United States.
Typical lead time:
14-21 working days.
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Further Information
3PK, MAPKAP-K3, MAPKAP3, MAPKAPK-3, MDPT3, MK-3, MAP kinase-activated protein kinase 3, MAPKAP kinase 3, chromosome 3p kinase, mitogen-activated protein kinase-activated protein kinase 3
WB: 1:500 - 1:2000
IF: 1:50 - 1:200
This gene encodes a member of the Ser/Thr protein kinase family. This kinase functions as a mitogen-activated protein kinase (MAP kinase)- activated protein kinase. MAP kinases are also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This kinase was shown to be activated by growth inducers and stress stimulation of cells. In vitro studies demonstrated that ERK, p38 MAP kinase and Jun N-terminal kinase were all able to phosphorylate and activate this kinase, which suggested the role of this kinase as an integrative element of signaling in both mitogen and stress responses. This kinase was reported to interact with, phosphorylate and repress the activity of E47, which is a basic helix-loop-helix transcription factor known to be involved in the regulation of tissue-specific gene expression and cell differentiation. Alternate splicing results in multiple transcript variants that encode the same protein.
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human MAPKAPK3 (NP_004626.1).
7867
MAPK activated protein kinase 3
MAPKAPK3
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
Observed: 38kDa
Affinity purification
Cell Cycle, Immunology, Signal Transduction
Q16644
Optimal dilutions for each application to be determined by the researcher.
Antibody is Knockout validated.