IDH3B Antibody

isocitric dehydrogenase subunit beta, isocitrate dehydrogenase, NAD(+)-specific, mitochondrial, beta subunit, isocitrate dehydrogenase [NAD] subunit beta, NAD+-specific isocitrate dehydrogenase beta, NAD+-specific isocitrate dehydrogenase b subunit, NAD+-specific ICDH, NAD(+)-specific ICDH subunit beta, RP46, MGC903, H-IDHB, FLJ11043, isocitrate dehydrogenase 3 (NAD+) beta, IDH3B

WB: 1:500 - 1:2000

IHC: 1:50 - 1:100

IF: 1:50 - 1:100

Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the beta subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

batch dependent

Unconjugated

Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

Recombinant fusion protein containing a sequence corresponding to amino acids 35-170 of human IDH3B (NP_008830.2).

3420

isocitrate dehydrogenase 3 (NAD+) beta

IDH3B

Homo sapiens

Liquid

Observed: 42kDa

Affinity purification

Cancer, Signal Transduction

O43837

Optimal dilutions for each application to be determined by the researcher.