ProSci

PRDM2 Antibody

Product Code:
 
PSI-14-825
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Shipping:
 
Blue Ice or RT
Storage:
 
Store at -20°C. Avoid freeze / thaw cycles.
1 / 1
Western blot analysis of extracts of various cell lines, using PRDM2 antibody (14-825) at 1:3000 dilution.<br/>Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.<br/>Lysates/proteins: 25ug per lane.<br/>Blocking buffer: 3% nonfat dry milk in TBST.<br/>Detection: ECL Basic Kit.<br/>Exposure time: 90s.

Western blot analysis of extracts of various cell lines, using PRDM2 antibody (14-825) at 1:3000 dilution.<br/>Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.<br/>Lysates/proteins: 25ug per lane.<br/>Blocking buffer: 3% nonfat dry milk in TBST.<br/>Detection: ECL Basic Kit.<br/>Exposure time: 90s.

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PSI-14-825-50uL50uL£433.00
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This product comes from: United States.
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Further Information

Additional Names:
HUMHOXY1, KMT8, KMT8A, MTB-ZF, RIZ, RIZ1, RIZ2, PR domain zinc finger protein 2, GATA-3 binding protein G3B, MTE-binding protein, PR domain 2, PR domain containing 2, with ZNF domain, PR domain-containing protein 2, lysine N-methyltransferase 8, retinoblastoma protein-binding zinc finger protein, retinoblastoma protein-interacting zinc finger protein, zinc finger protein RIZ, zinc-finger DNA-binding protein
Application Note:
WB: 1:500 - 1:2000
Background:
This tumor suppressor gene is a member of a nuclear histone/protein methyltransferase superfamily. It encodes a zinc finger protein that can bind to retinoblastoma protein, estrogen receptor, and the TPA-responsive element (MTE) of the heme-oxygenase-1 gene. Although the functions of this protein have not been fully characterized, it may (1) play a role in transcriptional regulation during neuronal differentiation and pathogenesis of retinoblastoma, (2) act as a transcriptional activator of the heme-oxygenase-1 gene, and (3) be a specific effector of estrogen action. Multiple transcript variants encoding different isoforms have been found for this gene.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 50-150 of human PRDM2 (NP_036363.2).
NCBI Gene ID #:
7799
NCBI Official Name:
PR/SET domain 2
NCBI Official Symbol:
PRDM2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
Observed: 300kDa
Purification:
Affinity purification
Research Area:
Cancer, Neuroscience
Swissprot #:
Q13029
User NOte:
Optimal dilutions for each application to be determined by the researcher.