Further Information
CHDS6, matrix metallopeptidase 3 (stromelysin 1, progelatinase), matrix metalloproteinase 3 (stromelysin 1, matrix metalloproteinase-3, MGC126102, MGC126103, MGC126104, MMP3, MMP-3, OTTHUMP00000045949, proteoglycan, SL-1, STMY, STMY1, STR1
WB: 1:500 - 1:2000
IF: 1:50 - 1:100
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades fibronectin, laminin, collagens III, IV, IX, and X, and cartilage proteoglycans. The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Recombinant fusion protein containing a sequence corresponding to amino acids 248-477 of human MMP3 (NP_002413.1).
4314
matrix metallopeptidase 3 (stromelysin 1, progelatinase)
MMP3
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
Observed: 54kDa
Affinity purification
Cancer, Cell Cycle, Signal Transduction
P08254
Optimal dilutions for each application to be determined by the researcher.