Further Information
IKBZ, INAP, MAIL, NF-kappa-B inhibitor zeta, I-kappa-B-zeta, IL-1 inducible nuclear ankyrin-repeat protein, Ikappa B-zeta variant 3, IkappaB-zeta, ikB-zeta, ikappaBzeta, molecule possessing ankyrin repeats induced by lipopolysaccharide, nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
WB: 1:500 - 1:2000
IF: 1:50 - 1:200
This gene is a member of the ankyrin-repeat family and is induced by lipopolysaccharide (LPS). The C-terminal portion of the encoded product which contains the ankyrin repeats, shares high sequence similarity with the I kappa B family of proteins. The latter are known to play a role in inflammatory responses to LPS by their interaction with NF-B proteins through ankyrin-repeat domains. Studies in mouse indicate that this gene product is one of the nuclear I kappa B proteins and an activator of IL-6 production. Two transcript variants encoding different isoforms have been found for this gene.
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human NFKBIZ (NP_113607.1).
64332
NFKB inhibitor zeta
NFKBIZ
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
Observed: 68-90kDa
Affinity purification
Apoptosis, Cell Cycle, Immunology, Innate Immunity, Transcription
Q9BYH8
Optimal dilutions for each application to be determined by the researcher.
