Further Information
NaG, Nav2.1, Nav2.2, SCN6A, sodium channel protein type 7 subunit alpha, putative voltage-gated sodium channel subunit alpha Nax, sodium channel protein cardiac and skeletal muscle subunit alpha, sodium channel protein type VII subunit alpha, sodium channel, voltage-gated, type VI, alpha polypeptide, sodium channel, voltage-gated, type VII, alpha subunit, voltage-dependent sodium channel alpha subunit
WB: 1:500 - 1:2000
This gene encodes one of the many voltage-gated sodium channel proteins. For proper functioning of neurons and muscles during action potentials, voltage-gated sodium channels direct sodium ion diffusion for membrane depolarization. This sodium channel protein has some atypical characteristics; the similarity between the human and mouse proteins is lower compared to other orthologous sodium channel pairs. Also, the S4 segments, which sense voltage changes, have fewer positive charged residues that in other sodium channels; domain 4 has fewer arginine and lysine residues compared to other sodium channel proteins. Several alternatively spliced transcript variants exist, but the full-length natures of all of them remain unknown.
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Recombinant fusion protein containing a sequence corresponding to amino acids 265-368 of human SCN7A (NP_002967.2).
6332
sodium voltage-gated channel alpha subunit 7
SCN7A
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
Observed: 260kDa
Affinity purification
Neuroscience
Q01118
Optimal dilutions for each application to be determined by the researcher.