Antibody Clonality:
Polyclonal
Storage:
Store at 4°C. Avoid freeze / thaw cycles.
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This product comes from:
United States.
Typical lead time:
14-21 working days.
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Further Information
Protein disulfide isomerase family A member 1, DSI, GIT, PDI, PHDB, PO4DB, PO4HB, PROHB, ERBA2L, P4Hbeta
WB: 1:500 - 1:1000
IHC: 1:50 - 1:200
Flow: 1:20 - 1:50
This gene encodes the beta subunit of prolyl 4-hydroxylase, a highly abundant multifunctional enzyme that belongs to the protein disulfide isomerase family. When present as a tetramer consisting of two alpha and two beta subunits, this enzyme is involved in hydroxylation of prolyl residues in preprocollagen. This enzyme is also a disulfide isomerase containing two thioredoxin domains that catalyze the formation, breakage and rearrangement of disulfide bonds. Other known functions include its ability to act as a chaperone that inhibits aggregation of misfolded proteins in a concentration-dependent manner, its ability to bind thyroid hormone, its role in both the influx and efflux of S-nitrosothiol-bound nitric oxide, and its function as a subunit of the microsomal triglyceride transfer protein complex.
PBS with 0.02% sodium azide, pH7.3.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
A synthetic peptide of human P4HB
5034
prolyl 4-hydroxylase, beta polypeptid
P4HB
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
Observed: 57kDa
Affinity purification
Cancer, Cell Cycle, Signal Transduction
P07237
Optimal dilutions for each application to be determined by the researcher.