Antibody Clonality:
Polyclonal
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
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This product comes from:
United States.
Typical lead time:
14-21 working days.
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Further Information
TP53, P53, BCC7, LFS1, TRP53
WB: 1:500 - 1:2000
IHC: 1:50 - 1:200
IF: 1:50 - 1:200
ChIP: 1:50 - 1:100
This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277).
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Recombinant fusion protein containing a sequence corresponding to amino acids 1-110 of human p53 (NP_000537.3).
7157
tumor protein p53
TP53
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
Observed: 53kDa
Affinity purification
Apoptosis, Cancer, Cell Cycle, Neuroscience, Signal Transduction, Transcription
P04637
Optimal dilutions for each application to be determined by the researcher.