Clomiphene citrate
Product Code:
CDX-C0696
CDX-C0696
Antibody Isotype:
n/a
n/a
Antibody Clone:
n/a
n/a
Regulatory Status:
RUO
RUO
Shipping:
Ambient
Ambient
Storage:
+4°C
+4°C
No additional charges, what you see is what you pay! *
| Code | Size | Price |
|---|
| CDX-C0696-G001 | 1 g | £41.00 |
Quantity:
| CDX-C0696-G005 | 5 g | £121.00 |
Quantity:
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* Rare exceptions are clearly labelled (only 0.14% of items!).
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This product comes from: Switzerland.
Typical lead time: 7-10 working days.
Contact us for more accurate information.
Typical lead time: 7-10 working days.
Contact us for more accurate information.
- Further Information
- Documents
- References
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Further Information
Alternate Names/Synonyms:
Clomifene; Omifin; NSC 35770; 2-(4-[2-Chloro-1,2-diphenylethenyl]phenoxy)-N,N-diethylethanamine; Clomiphene citrate salt
Appearance:
Solid.
CAS:
50-41-9
EClass:
32160000
Form (Short):
liquid
GHS Symbol:
GHS08
Handling Advice:
Protect from light and moisture.
Hazards:
H361
InChi:
InChI=1S/C26H28ClNO.C6H8O7/c1-3-28(4-2)19-20-29-24-17-15-22(16-18-24)25(21-11-7-5-8-12-21)26(27)23-13-9-6-10-14-23;7-3(8)1-6(13,5(11)12)2-4(9)10/h5-18H,3-4,19-20H2,1-2H3;13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)/b26-25+;
InChiKey:
PYTMYKVIJXPNBD-BTKVJIOYSA-N
Long Description:
Chemical. CAS: 50-41-9. Formula: C26H28ClNO . C6H8O7. MW: 598.08. Clomiphene is a nonsteroidal triphenylethylene derivative. It acts as a selective estrogen receptor modulator (SERM), that impairs the activation of estrogen receptors (ERs) by 17beta-estradiol, similar to tamoxifen and raloxifene. It potently binds both ERalpha and ERbeta (Ki = 0.9 and 1.2nM, respectively). Clomiphene enhances the release of gonadotropin-releasing hormone, stimulating the release of follicle-stimulating hormone and luteinizing hormone, culminating in ovulation. Triphenylethylene antiestrogens may also be used as antileukemic drugs which kill cells by apoptosis mediated by oxidative stress and activation of PKC.
MDL:
MFCD00058322
Molecular Formula:
C26H28ClNO . C6H8O7
Molecular Weight:
598.08
Package Type:
Vial
Precautions:
P281
Product Description:
Clomiphene is a nonsteroidal triphenylethylene derivative. It acts as a selective estrogen receptor modulator (SERM), that impairs the activation of estrogen receptors (ERs) by 17beta-estradiol, similar to tamoxifen and raloxifene. It potently binds both ERalpha and ERbeta (Ki = 0.9 and 1.2nM, respectively). Clomiphene enhances the release of gonadotropin-releasing hormone, stimulating the release of follicle-stimulating hormone and luteinizing hormone, culminating in ovulation. Triphenylethylene antiestrogens may also be used as antileukemic drugs which kill cells by apoptosis mediated by oxidative stress and activation of PKC.
Purity:
>98% (HPLC)
Signal word:
Warning
SMILES:
Cl/C(C1=CC=CC=C1)=C(C2=CC=CC=C2)/C3=CC=C(OCCN(CC)CC)C=C3.OC(CC(C(O)=O)(O)CC(O)=O)=O
Solubility Chemicals:
Soluble in DMOS or DMF. Slightly soluble in water, methanol or chloroform.
Source / Host:
Synthetic.
Transportation:
Non-hazardous
UNSPSC Category:
Biochemical Reagents
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at +4°C.
Documents
References
(1) J.H. Clark & B.M. Markaverich; Pharmacol. Ther. 15, 467 (1981) | (2) E.Y. Adashi; Fertil. Steril. 42, 331 (1984) | (3) E. Kousta, et al.; Hum. Reprod. Update 3, 359 (1997) | (4) G.G.J.M. Kuiper, et al.; Endocrinology 138, 863 (1997) | (5) T. Hayon, et al.; Anticancer Res. 19, 2089 (1999) | (6) S.G. Haskell; South Med. J. 96, 469 (2003) | (7) R. Homburg; Hum. Reprod. 20, 2043 (2005) | (8) M. Amita, et al.; Endocrinology 151, 394 (2010)